A car bomb has targeted the convoy of Egypt's Interior Minister Mohammed Ibrahim but failed to harm the politician, the security forces say.
At least four people were reported injured in the blast, which media reports call an assassination attempt.
State-run al-Ahram paper said the minister's convoy was targeted as it travelled through Nasr City.
Nasr City is a stronghold of the Islamist Muslim Brotherhood group, but there is no word on who was involved.
The explosion took place at around 10:30 local time (08:30 GMT) near Mr Ibrahim's home.
Quoting security sources, state-run Mena news agency said a booby-trapped car exploded in Mustafa al-Nahas street, Nasr City district, as the minister was en route from his home to the ministry.
Pictures uploaded to the internet by witnesses showed substantial damage to a building next to the blast.
Egyptian police have reportedly killed two of the attackers, security sources told Reuters news agency.
The interior minister is in charge of the country's police force, which alongside security forces, carried out a deadly security crack down in the capital last month, clearing two protest camps set up by Muslim Brotherhood supporters of ousted President Mohammed Morsi.
Nasr City was the site of the larger of the two protest camps based outside Rabaa al-Adawiya mosque, which was dismantled in the security operation on 14 August.
The BBC's Bethany Bell says there has been a lot of Muslim Brotherhood activity in the area over the last couple of weeks.
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